La tromboelastografia attivata con caolino nel cane sano ed in quello leishmaniotico
Kaolin-activated thromboelastography in healthy and leishmaniotic dogs
Ambrosio R., Sannino M. L., Borbone P., Cortese L.
Dipartimento di Scienze Cliniche Veterinarie – Sezione di Clinica Medica, Università degli Studi di Napoli Federico II - Italy
Thromboelastography (TEG) is an analytical method for assessing global hemostasis. When used together with specific activators such as Kaolin, Celite or Tissue Factor, this method can evaluate hemostatic disorders in dog, and this animal’s predisposition to intravascular disseminated coagulation (DIC).
The objective of the present study is simplify the interpretation of data obtained from kaolin activated TEG analysis in dog.
Reference values for kaolin activated TEG analysis in healthy dog, namely, for R , K , α, MA , G and C.I., have been specified in previous studies of dog and man. The present study establishes its own reference values for kaolin activated TEG anaylsis in healthy dogs, and compares these reference values to kaolin activated TEG values found in leishmaniotic dogs.
These latter values are used to establish new reference values that indicate the presence of hyper-coagulation, an early stage of DIC often associated with leishmanosis.
thromboelastography, hemostasis, leishmaniosis, dog